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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
44.21
Human Site:
S250
Identified Species:
88.43
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
S250
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Chimpanzee
Pan troglodytes
XP_514697
253
28128
S250
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
Dog
Lupus familis
XP_853966
302
33650
S299
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
S241
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
S311
R
L
R
G
R
K
R
S
M
I
G
_
_
_
_
Frog
Xenopus laevis
NP_001089506
237
26742
S234
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
S228
R
L
R
G
R
K
R
S
M
V
G
_
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
T221
R
A
R
G
R
K
R
T
M
I
G
_
_
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
T223
R
Q
R
G
R
K
R
T
M
I
G
_
_
_
_
Maize
Zea mays
NP_001146448
226
25230
T223
R
Q
R
G
R
K
R
T
M
V
G
_
_
_
_
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
S258
R
L
R
G
R
K
R
S
M
L
G
_
_
_
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
N.A.
N.A.
N.A.
90.9
100
100
N.A.
72.7
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
100
N.A.
100
N.A.
N.A.
N.A.
100
100
100
N.A.
90.9
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
72.7
81.8
N.A.
N.A.
90.9
N.A.
P-Site Similarity:
90.9
90.9
N.A.
N.A.
100
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
92
0
0
0
0
0
0
92
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
92
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
67
0
0
0
0
0
0
0
9
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
92
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
92
0
92
0
92
0
92
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
59
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
92
92
92
92
% _